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Mutation Information
|
Mutation Site
|
N146S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
27031988
|
|
Disease
|
Occult HBV infection;
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
The Journal of general virology |
|
Title
|
Functional analysis of 'a' determinant mutations associated with occult HBV in HIV-positive South Africans. |
|
Author
|
Powell EA,Boyce CL,Gededzha MP,Selabe SG,Mphahlele MJ,Blackard JT |
|
Evidence
|
In contrast, N146S resulted in a significant increase in lysate HBsAg in both viral backgrounds. Transfection efficiency was not altered by the presence of occult-associated mutations, as shown in Fig. S1 (available in the online Supplementary Material).
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HBV Mutation Detail Information