HBV Mutation Detail Information

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Mutation Information

Mutation Site	N146S
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	A

Literature Information

PubMed PMID	20881037
Published Year	2010
Journal	Journal of virology
Title	Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site.
Author	Ito K,Qin Y,Guarnieri M,Garcia T,Kwei K,Mizokami M,Zhang J,Li J,Wands JR,Tong S
Evidence	DMSO treatment increased the signals of virion DNA for all the secretion-competent constructs, including the wild type and the M133T, I110M/M133T, M133T/G145R, M133T/N146Q, M133T/N146S, and M133T/R169H mutants (Fig. (Fig.7B7B and and8B).8B).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation