Mutation Information
Mutation Site
|
N146S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Country
|
Taiwan;China |
Literature Information
PubMed PMID
|
20210630
|
Disease
|
HBV infection
|
Published Year
|
2010 |
Journal
|
The Journal of infectious diseases |
Title
|
No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization. |
Author
|
Hsu HY,Chang MH,Ni YH,Chiang CL,Chen HL,Wu JF,Chen PJ |
Evidence
|
In the prior 3 surveys, serum HBV DNA level determined by signal-amplification nucleic acid probe assay (sensitivity, 1.0 pg/mL) was available in 3 such children (infected with T126A, T125A, and N146S, respectively) and found to be <1, 1.3, and 1.9 pg/mL, respectively.
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