Mutation Information
Mutation Site
|
N146S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
C |
Country
|
china |
Literature Information
PubMed PMID
|
11679975
|
Disease
|
Occult HBV infection
|
Published Year
|
2001 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
Prevalence of naturally occurring surface gene variants of hepatitis B virus in nonimmunized surface antigen-negative Chinese carriers. |
Author
|
Hou J,Wang Z,Cheng J,Lin Y,Lau GK,Sun J,Zhou F,Waters J,Karayiannis P,Luo K |
Evidence
|
These changes involved 11 positions inside and 5 outside of the historical first and second loops of the "a" determinant, and included the following: Q101K, T115A, K122N, T123A, T126N, Q129N, G130R, T131I, M133T, F134L, C138Y, K141E, P142S, G145R, N146S, and C147F/R.
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