HBV Mutation Detail Information

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Mutation Information
Mutation Site N146I
Mutation Type Amino acid level
Gene/Protein/Region Type S
Country Taiwan;China
Literature Information
PubMed PMID 20210630
Disease HBV infection
Published Year 2010
Journal The Journal of infectious diseases
Title No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization.
Author Hsu HY,Chang MH,Ni YH,Chiang CL,Chen HL,Wu JF,Chen PJ
Evidence In the 1999 survey, serum HBV DNA determined by real-time PCR in 2 HBsAg-negative mutant-infected patients (T131I and N146I) was <103 copies/mL for both patients, whereas a higher viral load was found in another 5 HBsAg (+), mutant-infected patients (range, 106.6–109 copies/mL).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation