Mutation Information
Mutation Site
|
N146D |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
B;C |
Country
|
China |
Literature Information
PubMed PMID
|
31516090
|
Disease
|
Occult HBV infection
|
Published Year
|
2019 |
Journal
|
Emerging microbes & infections |
Title
|
Occult HBV infection in Chinese blood donors: role of N-glycosylation mutations and amino acid substitutions in S protein transmembrane domains. |
Author
|
Zhang L,Chang L,Laperche S,Ji H,Zhao J,Jiang X,Wang L,Candotti D |
Evidence
|
Particularly, mutations removing the N146 glycosylation site (N146D/S/Y) were found in 4.4% (2/45) and 6% (3/50) of OBI genotype B (OBIB) and genotype C (OBIC) sequences, respectively.
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