|
Mutation Information
|
Mutation Site
|
N146D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Country
|
South Africa |
Literature Information
|
PubMed PMID
|
27031988
|
|
Disease
|
Occult HBV infection;
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
The Journal of general virology |
|
Title
|
Functional analysis of 'a' determinant mutations associated with occult HBV in HIV-positive South Africans. |
|
Author
|
Powell EA,Boyce CL,Gededzha MP,Selabe SG,Mphahlele MJ,Blackard JT |
|
Evidence
|
Of the seven mutations analysed, four (S132P, C138Y, N146D and C147Y) resulted in decreased HBsAg expression in one viral background but not in the second viral background.
|
|
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HBV Mutation Detail Information