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Mutation Information
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Mutation Site
|
N146A |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
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Viral Reference
|
V01460.1
|
Literature Information
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PubMed PMID
|
19570861
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virology |
|
Title
|
A function essential to viral entry underlies the hepatitis B virus "a" determinant. |
|
Author
|
Salisse J,Sureau C |
|
Evidence
|
Note that the N146A and T148A substitutions remove the signal for N glycosylation at position 146, leading to the detection of S- and L-HBsAg as unglycosylated forms only (M-HBsAg is detected as a glycosylated form bearing N- and O-linked carbohydrates in the pre-S2 domain).
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HBV Mutation Detail Information