|
Mutation Information
|
Mutation Site
|
N131T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
Literature Information
|
PubMed PMID
|
20881037
|
|
Published Year
|
2010 |
|
Journal
|
Journal of virology |
|
Title
|
Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site. |
|
Author
|
Ito K,Qin Y,Guarnieri M,Garcia T,Kwei K,Mizokami M,Zhang J,Li J,Wands JR,Tong S |
|
Evidence
|
Destroying this site by N131Q/T mutation or preventing glycosylation by tunicamycin treatment of transfected cells abrogated the effect of the M133T mutation.
|
|
|
HBV Mutation Detail Information