|
Mutation Information
|
Mutation Site
|
N131A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
DQ993693;
AB073827 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
28939157
|
|
Disease
|
HBV infection
|
|
Published Year
|
2017 |
|
Journal
|
Vaccine |
|
Title
|
Molecular evolution of hepatitis B vaccine escape variants in China, during 2000-2016. |
|
Author
|
Wang J,Qiu J,Zhu Y,Zhou H,Yu L,Ding Y,Zhang L,Guo Z,Dong C |
|
Evidence
|
Four sites (A5T/S, L21S, T/A126S and T/N131I/A) and 13 sites (N3S, T5A, G10Q/R/E, L21S, T47K/A/V, L98V/P, I/S126N/V/T, Q129H/R/L, T131P/I/N/A, G145A/R, L175S/F, L213I/S, V224A/G) were found to be under positive selection in genotype B and C HBV vaccine escape strains, respectively.
|
|
|
HBV Mutation Detail Information