HIV Mutation Detail Information

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Mutation Information
Mutation Site N126K
Mutation Type Amino acid level
Gene/Protein/Region Type Gp41
Country Spain
Literature Information
PubMed PMID 22333046
Clinical information Yes
Disease HIV infection/AIDS
Published Year 2012
Journal Retrovirology
Title The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype.
Author Cunyat F,Marfil S,García E,Svicher V,Pérez-Alvárez N,Curriu M,Perno CF,Clotet B,Blanco J,Cabrera C
Evidence Most of the recombinant plasmids constructed from sequences obtained during ENF treatment carried the V38A mutation as the only change associated with ENF resistance, although four clones derived from the 140N patient carried the N42T mutation, and three others showed the N126K mutation.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation