HIV Mutation Detail Information

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Mutation Information
Mutation Site M50I
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Relevant Drug INSTIs
Country South Africa;Cameroon
Literature Information
PubMed PMID 32858802
Disease HIV infection/AIDS
Published Year 2020
Journal Viruses
Title Structural Comparison of Diverse HIV-1 Subtypes using Molecular Modelling and Docking Analyses of Integrase Inhibitors.
Author Isaacs D,Mikasi SG,Obasa AE,Ikomey GM,Shityakov S,Cloete R,Jacobs GB
Evidence The alignment also showed 17 NOPs within a South African cohort-derived Subtype C consensus sequence, namely D25E, V31I, M50I, V72I, F100Y, L101I, T112V, T124A, T125A, K136Q, I151V, V201I, T218I, V234I, R269K, D278A, S283G (Supplementary Figure S1).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation