Mutation Information
Mutation Site
|
M50I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Country
|
Kenya |
Literature Information
PubMed PMID
|
32116431
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Ethiopian journal of health sciences |
Title
|
Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya. |
Author
|
Mabeya S,Nyamache A,Ngugi C,Nyerere A,Lihana R |
Evidence
|
However, polymorphic accessory mutations associated with reduced susceptibility of integrase inhibitors were observed in low frequency; M50I (12.2%), T97A (3.7%), S153YG, E92G (1.6%), G140S/A/C (1.1%) and E157Q (0.5%).
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