Mutation Information
Mutation Site
|
M46L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
bictegravir (BIC);emtricitabine (FTC);tenofovir alafenamide (TAF);dolutegravir (DTG) |
Literature Information
PubMed PMID
|
32701823
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
Title
|
Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) From Dolutegravir (DTG)+F/TAF or DTG+F/Tenofovir Disoproxil Fumarate (TDF) in the Presence of Pre-existing NRTI Resistance. |
Author
|
Acosta RK,Willkom M,Andreatta K,Liu H,Martin R,Parvangada A,Martin H,Collins S,White KL |
Evidence
|
Or E138A/G/K/Q/R in RT (Table 2).
|
|
|