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Mutation Information
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Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
G;unclassified subtype G |
|
Relevant Drug
|
atazanavir (ATV);darunavir (DRV);fosamprenavir (FPV);indinavir (IDV);lopinavir (LPV);nelfinavir (NFV);saquinavir (SQV);tipranavir (TPV);ritonavir |
|
Country
|
Nigeria |
Literature Information
|
PubMed PMID
|
32267869
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
Polymorphisms and drug resistance analysis of HIV-1 isolates from patients on first line antiretroviral therapy (ART) in South-eastern Nigeria. |
|
Author
|
Udeze AO,Olaleye DO,Odaibo GN |
|
Evidence
|
Major PI resistance-associated mutations were identified at two sites including M46L (16.7% of subtype G/UG) and V82L (6.3% of CRF02_AG).
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HIV Mutation Detail Information