|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
G |
|
Relevant Drug
|
PIs |
|
Country
|
Nigeria |
Literature Information
|
PubMed PMID
|
31959116
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
BMC microbiology |
|
Title
|
Low levels of HIV-1 drug resistance mutations in patients who achieved viral re-suppression without regimen switch: a retrospective study. |
|
Author
|
Onwuamah CK,Okpokwu J,Audu R,Imade G,Meloni ST,Okwuraiwe A,Chebu P,Musa AZ,Chaplin B,Dalhatu I,Agbaji O,Samuels J,Ezechi O,Ahmed M,Odaibo G,Olaleye DO,Okonkwo P,Salako BL,Raizes E,Yang C,Kanki PJ,Idigbe EO |
|
Evidence
|
Two patients (4% of 57) had DRMs to protease inhibitors (PIs): one patient had M46 L (major PI DRM) while the other patient had L23I (minor PI DRM).
|
|
|
HIV Mutation Detail Information