HIV Mutation Detail Information

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Mutation Information
Mutation Site M46L
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Genotype/Subtype B;CRF01_AE;CRF07_BC;CRF08_BC
Relevant Drug PIs
Country China
Literature Information
PubMed PMID 31922125
Disease HIV infection/AIDS
Published Year 2020
Journal EClinicalMedicine
Title Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017).
Author Zuo L,Liu K,Liu H,Hu Y,Zhang Z,Qin J,Xu Q,Peng K,Jin X,Wang JH,Zhang C
Evidence Furthermore, we found a very high proportion (29.4%) of PI mutation M46I/L in ART-naïve individuals, significantly higher than that in ART-treated individuals (1.3%) (Fig. 4).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation