Mutation Information
Mutation Site
|
M46L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Genotype/Subtype
|
B;CRF01_AE;CRF07_BC;CRF08_BC |
Relevant Drug
|
PIs |
Country
|
China |
Literature Information
PubMed PMID
|
31922125
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
EClinicalMedicine |
Title
|
Trend of HIV-1 drug resistance in China: A systematic review and meta-analysis of data accumulated over 17 years (2001-2017). |
Author
|
Zuo L,Liu K,Liu H,Hu Y,Zhang Z,Qin J,Xu Q,Peng K,Jin X,Wang JH,Zhang C |
Evidence
|
Furthermore, we found a very high proportion (29.4%) of PI mutation M46I/L in ART-naïve individuals, significantly higher than that in ART-treated individuals (1.3%) (Fig. 4).
|
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