HIV Mutation Detail Information

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Mutation Information

Mutation Site	M46L
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Genotype/Subtype	F1
Country	Cyprus

Literature Information

PubMed PMID	29684083
Clinical information	Yes
Disease	HIV infection/AIDS
Published Year	2018
Journal	PloS one
Title	HIV-1 transmission networks across Cyprus (2010-2012).
Author	Kostrikis LG,Hezka J,Stylianou DC,Kostaki E,Andreou M,Kousiappa I,Paraskevis D,Demetriades I
Evidence	There were only three newly diagnosed patients with transmitted drug resistant HIV-1 strains, one study subject from the United Kingdom infected with subtype B strain and one from Romania with sub-subtype A2 strain, both with PI drug resistance mutation M46L and one from Greece with sub-subtype A1 with non-nucleoside reverse transcriptase inhibitors (NNRTI) drug resistance mutation K103N.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation