|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
tipranavir (TPV) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27997554
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
PloS one |
|
Title
|
Drug Resistance and Virological Failure among HIV-Infected Patients after a Decade of Antiretroviral Treatment Expansion in Eight Provinces of China. |
|
Author
|
Zuo Z,Liang S,Sun X,Bussell S,Yan J,Kan W,Leng X,Liao L,Ruan Y,Shao Y,Xing H |
|
Evidence
|
NRTIs mutations were most frequently seen as M184I/V (66.7%) and K65R (39.4%) in the RT region, while PI mutations were only found to be M46L in the protease (PR) region.
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HIV Mutation Detail Information