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Mutation Information

Mutation Site	M46L
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	Turkey

Literature Information

PubMed PMID	25397495
Disease	HIV infection/AIDS
Published Year	2014
Journal	Journal of the International AIDS Society
Title	Transmitted antiretroviral drug resistance mutations in newly diagnosed HIV-1 positive patients in Turkey.
Author	Sayan M,Sargýn F,Inan D,Sevgi DY,Celikbas AK,Yasar K,Kaptan F,Kutlu SS,Fýsgýn NT,Inci A,Ceran N,Karaoðlan Y,Cagatay A,Celen MK,Koruk ST,Ceylan B,Yýldýrmak T,Akalýn H,Korten V,Willke A
Evidence	The patients had TDRMs to NRTIs (K65R, M184V), NNRTIs (K101E, K103N/S, G190A/E/S, Y181I/C, Y188H/L) and PIs (M46L, I54V, L76V, V82L/T, N83D, I84V, L90M). The prevalence of overall TDRMs was 6.7% (52/774).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation