|
Mutation Information
|
Mutation Site
|
M46L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
A |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
25259833
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
|
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
|
Evidence
|
Of the 243 patients who received one or more protease inhibitors, 32 (13%) had a study-defined protease inhibitor-resistance mutation most commonly L10F, K20T, V32I, L33F, M46I/L, I47V/A, I50L, F53L, I54V/L, Q58E, L76V, V82A/C, I84V, L89V, and L90M.
|
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HIV Mutation Detail Information