HIV Mutation Detail Information

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Mutation Information
Mutation Site M46L
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Genotype/Subtype B;F1
Country Brazilian
Literature Information
PubMed PMID 18992847
Disease HIV infection/AIDS
Published Year 2009
Journal Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Title Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure.
Author Dumans AT,Barreto CC,Santos AF,Arruda M,Sousa TM,Machado ES,Sabino EC,Brindeiro RM,Tanuri A,Duarte AJ,Soares MA
Evidence Of note, M46I was more frequent than M46L in subtype B isolates, while M46L was more frequent than M46I in subtype F1 isolates (Table 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation