|
Mutation Information
|
Mutation Site
|
M46I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
B |
|
Viral Reference
|
HXB2
|
|
Relevant Drug
|
PIs |
Literature Information
|
PubMed PMID
|
33635848
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
AIDS (London, England) |
|
Title
|
Drug resistance mutations in HIV provirus are associated with defective proviral genomes with hypermutation. |
|
Author
|
Li Y,Etemad B,Dele-Oni R,Sharaf R,Gao C,Lichterfeld M,Li JZ |
|
Evidence
|
Certain Apolipoprotein B Editing Complex 3-related DRMs including reverse transcriptase gene mutations M184I, E138K, M230I, G190E and protease gene mutations M46I, D30N were enriched in hypermutated sequences but not in intact sequences or plasma sequences.
|
|
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HIV Mutation Detail Information