HIV Mutation Detail Information

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Mutation Information
Mutation Site M46I
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Genotype/Subtype B
Viral Reference HXB2
Relevant Drug PIs
Literature Information
PubMed PMID 33635848
Disease HIV infection/AIDS
Published Year 2021
Journal AIDS (London, England)
Title Drug resistance mutations in HIV provirus are associated with defective proviral genomes with hypermutation.
Author Li Y,Etemad B,Dele-Oni R,Sharaf R,Gao C,Lichterfeld M,Li JZ
Evidence Certain Apolipoprotein B Editing Complex 3-related DRMs including reverse transcriptase gene mutations M184I, E138K, M230I, G190E and protease gene mutations M46I, D30N were enriched in hypermutated sequences but not in intact sequences or plasma sequences.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation