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Mutation Information
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Mutation Site
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M46I |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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PR |
Literature Information
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PubMed PMID
|
33093566
|
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Published Year
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2020 |
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Journal
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Scientific reports |
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Title
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Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses. |
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Author
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Bonar MM,Tabler CO,Haqqani AA,Lapointe LE,Galiatsos JA,Joussef-Piña S,Quiñones-Mateu ME,Tilton JC |
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Evidence
|
3'Gag + Pol Virus 08-180 had seven major resistance mutations in PR: V32I, M46I, I47V, I54L, V82T, I84V, and L90M and five accessory mutations: K20T, L33F, K43T, G73S, and L89V and was predicted to have high-level resistance to all PIs.
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HIV Mutation Detail Information