HIV Mutation Detail Information

> M46I Search Result

Mutation Information

Mutation Site	M46I
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	atazanavir (ATV);fosamprenavir (FPV);indinavir (IDV);lopinavir (LPV);saquinavir (SQV);nelfinavir (NFV)
Country	USA

Literature Information

PubMed PMID	32371875
Disease	HIV infection/AIDS
Published Year	2020
Journal	Scientific reports
Title	HIV-1 molecular epidemiology and drug resistance-associated mutations among treatment-naïve blood donors in China.
Author	Zhao J,Lv X,Chang L,Ji H,Harris BJ,Zhang L,Jiang X,Guo F,Hackett J Jr,Yin P,Cloherty GA,Rodgers MA,Wang L
Evidence	Furthermore, 4 HIV-1 isolates (2.4%, 4/168) had surveillance drug-resistance mutation (SDRM), including 3 nonnucleosidereverse transcriptase inhibitors (NNRTI) SDRMs (1 K101E, 2 K103N) and 1 protease inhibitor (PI) SDRM (M46I).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation