|
Mutation Information
|
Mutation Site
|
M46I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
atazanavir (ATV);ritonavir;lopinavir(LPV) |
|
Country
|
Brazilian |
Literature Information
|
PubMed PMID
|
32218587
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
Characterization of HIV-1 genetic diversity and antiretroviral resistance in the state of Maranhão, Northeast Brazil. |
|
Author
|
Leal É,Arrais CR,Barreiros M,Farias Rodrigues JK,Silva Sousa NP,Duarte Costa D,Rodrigo Pereira Santos FD,Dantas Silva A,Silva Viana AIE,Barros AK,Lima K |
|
Evidence
|
The main resistance mutations that we identified were D30N, M46I, I54LV, V82A, N88D, and L90M for PIs;M41L, K65R, D67N, K70R, M184V, L210W, and T215FY for NRTIs;and L100I, K103N, and G190A for NNRTIs.
|
|
|
HIV Mutation Detail Information