|
Mutation Information
|
Mutation Site
|
M46I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
PIs;lopinavir (LPV);ritonavir |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32183889
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Virology journal |
|
Title
|
Prevalence of acquired drug resistance mutations in antiretroviral- experiencing subjects from 2012 to 2017 in Hunan Province of central South China. |
|
Author
|
Zou X,He J,Zheng J,Malmgren R,Li W,Wei X,Zhang G,Chen X |
|
Evidence
|
The proportion of PI-associated DRMs showed a tendency to increase from 2012 to 2017(0, 0, 0.22, 0.98, 1.86 and 3.81%). The major mutations were I54L (3.83%), V82L (2.84%) and M46I/L (1.53%).
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HIV Mutation Detail Information