HIV Mutation Detail Information

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Mutation Information

Mutation Site	M46I
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs

Literature Information

PubMed PMID	32082657
Disease	HIV infection/AIDS
Published Year	2020
Journal	Case reports in hepatology
Title	Successful Kidney Transplantation in a Recipient Coinfected with Hepatitis C Genotype 2 and HIV from a Donor Infected with Hepatitis C Genotype 1 in the Direct-Acting Antiviral Era.
Author	Farmakiotis D,Weiss Z,Brotherton AL,Morrissey P,Gohh R,Vieira K,Taylor LE,Garland JM
Evidence	He had been on numerous prior antiretroviral regimens to treat his HIV and harbored multiclass resistance to agents in the nonnucleoside reverse transcriptase inhibitor (NRTI: M184V and T215N/S/Y) and protease inhibitor (PI: L33I, M46I, I54V, I62V, and V82A/I/T) classes.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation