|
Mutation Information
|
Mutation Site
|
M46I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
CRF02_AG |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
PIs |
|
Country
|
Ghana |
Literature Information
|
PubMed PMID
|
32049783
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Medicine |
|
Title
|
High resistance to reverse transcriptase inhibitors among persons infected with human immunodeficiency virus type 1 subtype circulating recombinant form 02_AG in Ghana and on antiretroviral therapy. |
|
Author
|
Deletsu SD,Maina EK,Quaye O,Ampofo WK,Awandare GA,Bonney EY |
|
Evidence
|
Additionally, and at a lower level, protease inhibitor (PI)-resistance mutations, M46I, I54 V, V82A, L90 M, and I471 V, were also present in the sequences from antiretroviral therapy (ART)-experienced individuals.
|
|
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HIV Mutation Detail Information