HIV Mutation Detail Information

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Mutation Information

Mutation Site	M46I
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	Germany

Literature Information

PubMed PMID	30408827
Disease	HIV infection/AIDS
Published Year	2018
Journal	PloS one
Title	Increasing proportions of HIV-1 non-B subtypes and of NNRTI resistance between 2013 and 2016 in Germany: Results from the national molecular surveillance of new HIV-diagnoses.
Author	Hauser A,Hofmann A,Meixenberger K,Altmann B,Hanke K,Bremer V,Bartmeyer B,Bannert N
Evidence	PI-mutations M46I/L and V82L that are responsible for low or intermediate resistance levels to tipranavir, nelfinavir and fosamprenavir (Fig 3B) were also frequently present (Table 4) but without identifiable tendency during the study period (Fig 3A).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation