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Mutation Information
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Mutation Site
|
M46I |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
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Genotype/Subtype
|
B |
|
Relevant Drug
|
tenofovir (TDF);darunavir (DRV);ritonavir;tipranavir (TPV);atazanavir (ATZ);indinavir (IDV);abacavir (ABC);stavudine (D4T);didanosine (DDI);emtricitabine (FTC);saquinavir (SQV);zidovudine (ZVD);lamivudine (LAM);emtricitabine (FTC);efavirenz (EFV);nevirapine (NPV);fosamprenavir (FPV);nelfinavir (NFV);lopinavir (LPV) |
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Country
|
Brazil |
Literature Information
|
PubMed PMID
|
27338425
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2016 |
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Journal
|
International journal of environmental research and public health |
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Title
|
Viral Suppression and Resistance in a Cohort of Perinatally-HIV Infected (PHIV+) Pregnant Women. |
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Author
|
Cruz ML,Santos E,Benamor Teixeira Mde L,Poletti M,Sousa C,Gouvea MI,Nielsen-Saines K,João E |
|
Evidence
|
The most frequent major mutations were K103N, M184V, T215, M41L, D67N at reverse transcriptase gene and M46, I54V and V82A at protease gene.
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HIV Mutation Detail Information