Mutation Information
Mutation Site
|
M46I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Genotype/Subtype
|
B;F1 |
Country
|
Brazilian |
Literature Information
PubMed PMID
|
18992847
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2009 |
Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
Title
|
Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. |
Author
|
Dumans AT,Barreto CC,Santos AF,Arruda M,Sousa TM,Machado ES,Sabino EC,Brindeiro RM,Tanuri A,Duarte AJ,Soares MA |
Evidence
|
Of note, M46I was more frequent than M46L in subtype B isolates, while M46L was more frequent than M46I in subtype F1 isolates (Table 3).
|
|
|