HIV Mutation Detail Information

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Mutation Information
Mutation Site M46I
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Genotype/Subtype B
Relevant Drug PIs
Literature Information
PubMed PMID 17500586
Disease HIV infection/AIDS
Published Year 2007
Journal PLoS computational biology
Title HIV-1 subtype B protease and reverse transcriptase amino acid covariation.
Author Rhee SY,Liu TF,Holmes SP,Shafer RW
Evidence Different patterns of covariation were frequently observed for different mutations at the same position including the RT mutations T69D versus T69N, L74V versus L74I, V75I versus V75M, T215F versus T215Y, and K219Q/E versus K219N/R, and the protease mutations M46I versus M46L, I54V versus I54M/L, and N88D versus N88S.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation