HIV Mutation Detail Information

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Mutation Information

Mutation Site	M46I
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	Japan

Literature Information

PubMed PMID	17194486
Disease	HIV infection/AIDS
Published Year	2007
Journal	Antiviral research
Title	Drug-resistant HIV-1 prevalence in patients newly diagnosed with HIV/AIDS in Japan.
Author	Gatanaga H,Ibe S,Matsuda M,Yoshida S,Asagi T,Kondo M,Sadamasu K,Tsukada H,Masakane A,Mori H,Takata N,Minami R,Tateyama M,Koike T,Itoh T,Imai M,Nagashima M,Gejyo F,Ueda M,Hamaguchi M,Kojima Y,Shirasaka T,Kimura A,Yamamoto M,Fujita J,Oka S,Sugiura W
Evidence	Twenty-three cases, including three recently infected patients, were infected with HIV-1 having major drug-resistance mutations, including M41L, D67N, L100I, K103N, V106A, M184I, M184V, L210W, and revertant mutations at the 215 codon in reverse transcriptase and M46I in protease encoding regions.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation