HIV Mutation Detail Information

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Mutation Information

Mutation Site	M41L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs

Literature Information

PubMed PMID	33686573
Disease	HIV infection/AIDS
Published Year	2021
Journal	Infectious diseases and therapy
Title	Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People with HIV Aged ≥ 65 Years: Week 48 Results of a Phase 3b, Open-Label Trial.
Author	Maggiolo F,Rizzardini G,Molina JM,Pulido F,De Wit S,Vandekerckhove L,Berenguer J,D'Antoni ML,Blair C,Chuck SK,Piontkowsky D,Martin H,Haubrich R,McNicholl IR,Gallant J
Evidence	Primary NRTI-associated resistance mutations were observed in nine (10.7%) participants: of these, two had >= 3 thymidine analog mutations (TAMs) and three had M184V (two of whom also had >= 3 TAMs that included M41L).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation