|
Mutation Information
|
Mutation Site
|
M41L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
rilpivirine (RPV);lamivudine (LAM) |
|
Country
|
Singapore |
Literature Information
|
PubMed PMID
|
32438914
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
AIDS research and therapy |
|
Title
|
Efficacy and safety of abacavir/lamivudine plus rilpivirine as a first-line regimen in treatment-naïve HIV-1 infected adults. |
|
Author
|
Ho S,Wong JG,Ng OT,Lee CC,Leo YS,Lye DCB,Wong CS |
|
Evidence
|
These included M41L, D67N, M184V, T215Y, K101KE, E138EAG, Y181C, Y188YFHL, and M230ML mutations, many which are associated with high levels of reduced susceptibility to ABC/3TC as well as RPV.
|
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HIV Mutation Detail Information