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Mutation Information
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Mutation Site
|
M41L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B |
|
Relevant Drug
|
NRTIs |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
30151407
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
Open forum infectious diseases |
|
Title
|
Prevalence and Transmission Dynamics of HIV-1 Transmitted Drug Resistance in a Southeastern Cohort. |
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Author
|
Levintow SN,Okeke NL,Hué S,Mkumba L,Virkud A,Napravnik S,Sebastian J,Miller WC,Eron JJ,Dennis AM |
|
Evidence
|
For NRTI resistance, thymidine analogue mutations (TAMs) were most commonly observed, with T215Y/F/I/S/D/E/C/V mutations seen in 2.2% of patients (37/1658), followed by M41L in 1.2% (20/1658). M184V was seen in 0.5% (9/1658). Of the PI-associated mutations, L90M was seen in 0.8% of patients (13/1658).
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HIV Mutation Detail Information