|
Mutation Information
|
Mutation Site
|
M36I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
|
Country
|
Indonesia |
Literature Information
|
PubMed PMID
|
32874468
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Infectious disease reports |
|
Title
|
Detection of human immunodeficiency virus type 1 transmitted drug resistance among treatment-naive individuals residing in Jakarta, Indonesia. |
|
Author
|
Khairunisa SQ,Megasari NLA,Rahayu RP,Witaningrum AM,Ueda S,Yunifiar M MQ,Indriati DW,Kotaki T,Rusli A,Nasronudin,Kameoka M |
|
Evidence
|
Despite no drug resistance-related major mutations were identified, several drug resistance-related minor mutations including M36I [amino acid substitution from methionine (M) to isoleucine (I) at position 36 in the PR gene] (85.71%), H69K (85.71%), L89M (76.19%), K20R (57.14%), and G16E (47.62%), were detected in the PR genes (Table 1).
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HIV Mutation Detail Information