Mutation Information
Mutation Site
|
M29A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vif |
Literature Information
PubMed PMID
|
24422669
|
Published Year
|
2014 |
Journal
|
Retrovirology |
Title
|
HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3. |
Author
|
Evans SL,Schön A,Gao Q,Han X,Zhou X,Freire E,Yu XF |
Evidence
|
Also as expected, Vif mutant, H108A was incapable of binding Cul5, however maintained its ability to bind both Elo B/C and CBF-β (Figure 4A, lane 4).
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