HIV Mutation Detail Information

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Mutation Information
Mutation Site M230L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NRTIs
Country Spain
Literature Information
PubMed PMID 32030406
Disease HIV infection/AIDS
Published Year 2020
Journal The Journal of antimicrobial chemotherapy
Title The algorithm used for the interpretation of doravirine transmitted drug resistance strongly influences clinical practice and guideline recommendations.
Author Guerrero-Beltrán C,Martínez-Sanz J,Álvarez M,Olalla J,García-Álvarez M,Iribarren JA,Masiá M,Montero M,García-Bujalance S,Blanco JR,Rivero M,García-Fraile LJ,Espinosa N,Rodríguez C,Aguilera A,Vidal-Ampurdanes MC,Martínez M,Iborra A,Imaz A,Gómez-Sirvent JL,Peraire J,Portilla J,Caballero E,Alejos B,García F,Moreno S,CoRIS.
Evidence METHODS: We used the WHO 2009 list to investigate the prevalence of NNRTI, NRTI and PI TDR, in treatment-naive HIV-1-infected patients, adding mutations E138A/G/K/Q/R, V106I, V108I, V179L, G190Q, H221Y, F227C/L/V, M230IDR, L234I, P236L and Y318F in RT.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation