HIV Mutation Detail Information

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Mutation Information

Mutation Site	M230L
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs

Literature Information

PubMed PMID	20102272
Disease	HIV infection/AIDS
Published Year	2010
Journal	The Journal of infectious diseases
Title	Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients.
Author	Halvas EK,Wiegand A,Boltz VF,Kearney M,Nissley D,Wantman M,Hammer SM,Palmer S,Vaida F,Coffin JM,Mellors JW
Evidence	In subject 7N from the NNRTI-naive group (Fig 2A), a baseline sequence containing K103N clustered closely (bootstrap value 96) with sequences at failure containing K103N linked to Y188C or M230L.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation