HIV Mutation Detail Information

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Mutation Information
Mutation Site M230I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country Russia
Literature Information
PubMed PMID 33136751
Disease HIV infection/AIDS
Published Year 2020
Journal Journal of acquired immune deficiency syndromes (1999)
Title Long-Acting Injectable Cabotegravir + Rilpivirine for HIV Maintenance Therapy: Week 48 Pooled Analysis of Phase 3 ATLAS and FLAIR Trials.
Author Rizzardini G,Overton ET,Orkin C,Swindells S,Arasteh K,Górgolas Hernández-Mora M,Pokrovsky V,Girard PM,Oka S,Andrade-Villanueva JF,Richmond GJ,Baumgarten A,Masiá M,Latiff G,Griffith S,Harrington CM,Hudson KJ,St Clair M,Talarico CL,Patel P,Cutrell A,Van Eygen V,D'Amico R,Mrus JM,Wu S,Ford SL,Chow K,Roberts J,Wills A,Walters N,Vanveggel S,Van Solingen-Ristea R,Crauwels H,Smith KY,Spreen WR,Margolis DA
Evidence In ATLAS, there were 4 CVFs in the CAR arm, 3 of whom had reverse transcriptase mutations (M184I; M184V + G190S; and M230M/I) detected in HIV-1 RNA samples from 1 participant each, and 1 had no mutations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation