|
Mutation Information
|
Mutation Site
|
M230I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
30863788
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Open forum infectious diseases |
|
Title
|
Persistence of Human Immunodeficiency Virus-1 Drug Resistance Mutations in Proviral Deoxyribonucleic Acid After Virologic Failure of Efavirenz-Containing Antiretroviral Regimens. |
|
Author
|
De La Cruz J,Vardhanbhuti S,Sahoo MK,Rovner R,Bosch RJ,Manasa J,Katzenstein DA,Pinsky BA |
|
Evidence
|
We also used deep sequencing to analyze K103N and M184V levels within individuals to assess persistence and decay over time. In most cases, levels remained consistent within the categories of not detected, minority DRM (2%–20%), and >20%.
|
|
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HIV Mutation Detail Information