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Mutation Information
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Mutation Site
|
M204I |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Relevant Drug
|
entecavir (ETV);lamivudine (LAM);tenofovir alafenamide (TAF);islatravir (ISL);zidovudine (AZT) |
Literature Information
|
PubMed PMID
|
32080249
|
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Published Year
|
2020 |
|
Journal
|
Scientific reports |
|
Title
|
Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. |
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Author
|
Yasutake Y,Hattori SI,Tamura N,Matsuda K,Kohgo S,Maeda K,Mitsuya H |
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Evidence
|
These results strongly suggest that HBV’s resistance to 3TC and ETV (with M204V/L180M in HBV RT) is reasonably well simulated using an HIV-1 with HBV-associated 3MB mutation.
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HIV Mutation Detail Information