HBV Mutation Detail Information

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Mutation Information
Mutation Site M1V
Mutation Type Amino acid level
Gene/Protein/Region Type PreS2
Viral Reference AB697502; AB246345; JQ801515; AB246346; JQ801516; AB246339; AB900105; AB246342
Immune Escape Y
Country Japan
Literature Information
PubMed PMID 30584239
Disease HBV infection
Published Year 2018
Journal Scientific reports
Title Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
Author Inuzuka T,Ueda Y,Arasawa S,Takeda H,Matsumoto T,Osaki Y,Uemoto S,Seno H,Marusawa H
Evidence Furthermore, reactivated HBV in 11 of 16 (69%) non-HSCT cases possessed substitutions associated with impaired virion secretion, including E2G, L77R, L98V, T118K, and Q129H in the S region, and M1I/V in the PreS2 region.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation