|
Mutation Information
|
Mutation Site
|
M1T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS2 |
|
Genotype/Subtype
|
B;C |
|
Viral Reference
|
AB033550
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30835025
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2019 |
|
Journal
|
Digestive diseases and sciences |
|
Title
|
Pre-S/Surface and Core Promoter/Precore Mutations in Chronic Hepatitis B Patients with Severe Acute Exacerbation. |
|
Author
|
Chen YH,Lu SN,Wang JH,Hung CH,Hu TH,Chen CH |
|
Evidence
|
Multivariate analysis showed that the independent factors for SAE were V14G/A and L21S in surface genes, codons 109-119 deletions in pre-S1 genes, M1V/T/I in pre-S2 genes, and C1766T/T1768A and C1913A/G mutations in BCP/PC genes.
|
|
|
HBV Mutation Detail Information