HBV Mutation Detail Information

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Mutation Information

Mutation Site	M197T
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D
Viral Reference	X68292.1
Country	Italy

Literature Information

PubMed PMID	25452041
Disease	Chronic hepatitis B
Published Year	2015
Journal	The Journal of infection
Title	Specific mutations in the C-terminus domain of HBV surface antigen significantly correlate with low level of serum HBV-DNA in patients with chronic HBV infection.
Author	Mirabelli C,Surdo M,Van Hemert F,Lian Z,Salpini R,Cento V,Cortese MF,Aragri M,Pollicita M,Alteri C,Bertoli A,Berkhout B,Micheli V,Gubertini G,Santoro MM,Romano S,Visca M,Bernassola M,Longo R,De Sanctis GM,Trimoulet P,Fleury H,Marino N,Mazzotta F,Cappiello G,Spanò A,Sarrecchia C,Zhang JM,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V
Evidence	Results: Specific HBsAg-mutations (M197T,-S204N-Y206C/H-F220L) were significantly correlated with serum HBV-DNA <2000 IU/ml (posterior-probability>90%, P < 0.05).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation