Mutation Information
Mutation Site
|
M184V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
tenofovir (TDF);emtricitabine (FTC) |
Country
|
French |
Literature Information
PubMed PMID
|
33724373
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2021 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
Tenofovir disoproxil fumarate and emtricitabine maintenance strategy in virologically controlled adults with low HIV-1 DNA: 48 week results from a randomized, open-label, non-inferiority trial. |
Author
|
Prazuck T,Verdon R,Le Moal G,Ajana F,Bernard L,Sunder S,Roncato-Saberan M,Ponscarme D,Etienne M,Viard JP,Pasdeloup T,Darasteanu I,Pialoux G,de la Blanchardière A,Avettand-Fènoël V,Parienti JJ,Hocqueloux L,TRULIGHT Study Team . |
Evidence
|
Six VFs occurred in the tenofovir disoproxil fumarate/emtricitabine arm (two with emerging mutations M184V and K65R) versus two in the control arm (ITT difference 3.5%, 95% CI -1.9 to 9.4).
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