Mutation Information
Mutation Site
|
M184V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
A1;C;CRF10_CD;CRF35_AD;D |
Relevant Drug
|
zidovudine (AZT);lamivudine (LAM);efavirenz (EFV);stavudine (D4T);abacavir (ABC);lopinavir (LPV);zidovudine (ZVD);tenofovir (TDF);nevirapine (NPV);atazanavir (ATV);emtricitabine (FTC) |
Country
|
Northern Tanzania |
Literature Information
PubMed PMID
|
32986709
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
PloS one |
Title
|
Patterns of acquired HIV-1 drug resistance mutations and predictors of virological failure in Moshi, Northern Tanzania. |
Author
|
Mziray SR,Kumburu HH,Assey HB,Sonda TB,Mahande MJ,Msuya SE,Kiwelu IE |
Evidence
|
Frequent NNRTI-resistance associated mutations were K103N (n = 11), V106M (n = 5) and G190A (n = 5). Prevalent nucleoside analogue reverse transcriptase inhibitors-resistance associated mutations were M184V (n = 17), K70R (n = 7) and D67N (n = 6).
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