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Mutation Information
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Mutation Site
|
M184V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NRTIs;lopinavir (LPV);ritonavir |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
32183889
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
Virology journal |
|
Title
|
Prevalence of acquired drug resistance mutations in antiretroviral- experiencing subjects from 2012 to 2017 in Hunan Province of central South China. |
|
Author
|
Zou X,He J,Zheng J,Malmgren R,Li W,Wei X,Zhang G,Chen X |
|
Evidence
|
The most common primary NRTI mutations detected included M184V (62.04%), K65R (20.24%), K70R (15.01%), T215D/S (9.41%), Y115F (7.22%) and M41L (6.35%). The most frequent mutations to NNRTIs were K103N (41.90%), Y181C (28.12%), G190A (26.48%), K101E (11.71%), V106M/A (10.94%), V108I (7.44%), 221Y (7.22%) and Y188H (5.92%).
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HIV Mutation Detail Information